In our previous study, we used the transgenic lines Tg(lyz:eGFP) and Tg(mpeg:eGFP) to construct an inflammatory bowel diseases(IBD) model and a trauma model in zebrafish and successfully identified the active compounds in two herbal formulae, based on the endogenous imaging of immune cells [25,26]. The gene discussed is LYZ; the disease is inflammatory bowel disease.