The final results from the randomized phase 2 POPLAR and phase 3 OAK clinical trials, after a median follow-up of 48.6 months for POPLAR and 47.7 months for OAK, confirmed the survival benefit with Atezolizumab versus Docetaxel in patients with previously treated NSCLC, regardless of PD-L1 expression and histology [57]. The gene discussed is CD274; the disease is non-small cell lung carcinoma.