CXCL8 and benign prostatic hyperplasia: In prostate cells, through the primary culture of prostate basal cells, it can be found that the basal cells stimulated by IFN-γ and IL-17 have the main characteristics of antigen-presenting cells and produce pro-inflammatory cytokines and chemokines, such as IL-6, IL-8, and CXCL10, to promote the inflammation of BPH to form a positive feedback loop [58].