CNR2 and chronic cystitis: Based on our results showing higher protein expression of CB2 and PPARγ receptors compared to CB1 in urothelial cells (Figure 1C) and results from previous studies [37,38], identifying the CB2, but not CB1, receptor as a promising target to reduce symptoms of experimental cystitis and bladder inflammation in animal models, we speculated that CB2 and/or PPARγ are the receptors most probably targeted by CBD in SV-HUC1 cells.