PPARG and Bartsocas-Papas syndrome 1: Since terminally differentiated urothelial cells are absent or present only in limited numbers in the bladders of IC/BPS patients due to urothelial denudation [57] and PPARγ is also importantly involved in regulation of inflammatory response to urinary tract infection [69], we suggest that it might play an important, but not yet fully investigated, role in sustained inflammation, characteristic for IC/BPS.