Briefly, HR TB patients are subjects displaying significant proliferative responses, IFN-γ production and an increased percentage of SLAMF1+ CD3+ cells after Mtb-Ag stimulation; on the other hand, LR TB patients exhibit low proliferative responses, IFN-γ release and amounts of SLAMF1+ CD3+ cells. The gene discussed is SLAMF1; the disease is tuberculosis.