Zhang et al. [146] identified the lncRNA maternally expressed gene 3 (MEG3) levels in the blood and placental villi tissue of GDM patients and control pregnant people by RT-qPCR; they found that MEG3 expression levels were significantly upregulated in the GDM group, and MEG3 overexpression may target miR-345-3p and reduce its level, thereby inhibiting trophoblast cell migration and invasion and inducing apoptosis. The gene discussed is MEG3; the disease is gestational diabetes.