The central role of the Th2 response in the pathogenesis of eosinophilic esophagitis, with the release of mediators such as thymic stromal lymphopoietin (TSLP), IL-4, IL-5, IL-13, TGFß, and eosinophil chemokines (eotaxin 1-3/CCL11-CCL24-CCL26 and RANTES/CCL5) has been demonstrated [43]. This evidence concerns the gene CCL11 and eosinophilic esophagitis.