All the reported variants in CHST6, TACSTD2, UBIAD1, KRT12, PIKFYVE, GRHL2, AGBL1, and DCN caused macular corneal dystrophy (MCD), gelatinous drop-like corneal dystrophy (GDLD), Schnyder corneal dystrophy (SCD), Messman corneal dystrophy (MECD), Fleck corneal dystrophy (FCD), posterior polymorphous corneal dystrophy (PPCD), Fuchs endothelial corneal dystrophy (FECD), and congenital stromal corneal dystrophy (CSCD), respectively. The gene discussed is PIKFYVE; the disease is congenital stromal corneal dystrophy.