It has also been proven that the key factors involved in the development of CRC are proangiogenic molecules such as histamine, vascular endothelial growth factor (VEGF), tumour necrosis factor α (TNFA), or interleukin (IL) 6 and 8 (CXCL8) [5,7,10,20,22,24,25]. Here, VEGFA is linked to colorectal carcinoma.