The extended analysis of the subgroups (ASD+/Ob+, ASD+/Ob−, ASD−/Ob+, and ASD−/Ob−), stratified for gender, revealed no statistical significance in median leptin levels between females and males with overweight/obesity either before or after puberty (the ASD+/Ob+ and ASD−/Ob+ groups) (Table 5). Here, LEP is linked to obesity due to melanocortin 4 receptor deficiency.