ART4 and colorectal carcinoma: In addition, N-glycan diversity may be influenced by several factors, such as substrate availability for GTs and glycosidases in Golgi, nucleotide sugar metabolism, transport rates of the glycoprotein through the lumen of the ER and Golgi, and the proximity of an N-glycan attachment sequon to a transmembrane domain [68], which may also contribute to the unexpected observations between GTs and the glycosylation features in CRC cell lines.