The gut microbiota can modulate the immune system of the host through SCFAs or direct inhibition, and it is in this optic that we identified FAM168B, RAF1, HESX1, PIGC, and ENSGALT00000092369 as the top driver genes shared among body weight post-infection, Bacteroidetes relative abundance, and propionate and valerate cecal contents (Figure 8C). The gene discussed is HESX1; the disease is infection.