Figure 3B shows representative images of areas of high CD8 T cell infiltration in stage I and III melanomas. Remarkably, although we did not observe significant differences in the absolute numbers of CD8 T cells per 1 × 105 μm2 across the whole tumor specimen (Figure 3C), when we analyzed the percentage of CD8 T cells, we found a higher percentage of these cells in AM than in NACM (p = 0.0002). The percentage of CD8 T cells was still higher when we only considered early (I/II) (p = 0.04) or advanced (III/IV) (p = 0.001) stages (Figure 3E). The gene discussed is CD8A; the disease is melanoma.