Nine test items (including age, sex, HBV-DNA, HBeAg, ALT, LC, PLT, Alb, and AFP) incorporated into five previously reported HCC prediction models (REACH-B, GAG-HCC, PAGE-B, mPAGE-B, and APA-B) were examined to be associated with the development of HCC using BBJ samples. This evidence concerns the gene GPT and hepatocellular carcinoma.