Furthermore, vitexin at doses of 15, 30, and 60 mg/kg inactivated MAPK and NF-κB signaling pathways through the reduction of the protein expression of p38, ERK, and JNK, as well as the p65 subunit of NF-κB in Staphylococcus aureus-induced mastitis in mice [63]. Here, NFKB1 is linked to mastitis.