An increase in Nrf2, NQO1, and HO-1 was observed in H2O2-induced SH-SY5Y neuroblastoma cells after treatment with formononetin (50 μM) in vitro, as well as decreases in p65 NF-κB, TNF-α, IL-1β, IL-6, and MPO in tissues of gastric ulcers in Sprague–Dawley rats treated with formononetin at doses of 25 and 50 mg/kg [123,124]. The gene discussed is HMOX1; the disease is neuroblastoma.