A mouse model of pancreatic ischemia-reperfusion by vascular isolation of the distal pancreas for up to 30 min showed the upregulation of serum granulocyte-colony stimulating factor (G-CSF) IFN-γ, TNF- α, IL-2, IL-1β, IL-6, CCL2, CCL5, CXCL1, macrophage inflammatory protein 2 (MIP2) in the serum and upregulation of inflammatory molecules genes in pancreatic tissues [21]. The gene discussed is CSF3; the disease is ischemia.