The implication of IFN-γ on Mɸ in human skin is underlined by its effects on Mɸ immunologic reprofiling: in cutaneous sarcoidosis, IFN-γ-related expression of downstream translational targets includes STAT1, CEBPB, FN1, TREM1, CXCL9, CXCL10, IL-6, and others [45]. The gene discussed is IFNG; the disease is skin sarcoidosis.