SLC2A4 and type 2 diabetes mellitus: A double-blind randomized trial showed an improvement in the insulin sensitivity in T2D patients after 3 g/die of resveratrol per 12 weeks, with a significant increase in the SIRT1 and AMPK expressions in the skeletal muscle, which also determined an upregulation of the solute carrier family 2 member 4 (GLUT4) [68].