p73 shows the ability to influence the transcription of genes controlled by p53; for example, p21WAF1, mouse double minute 2 homolog (MDM2), B cell CLL/lymphoma2 (Bcl-2) Associated X-protein (BAX), 14-3-3s, and phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1, NOXA) [51,54]. The gene discussed is PMAIP1; the disease is B-cell chronic lymphocytic leukemia.