Top proteins identified, such as PLIN2 (FC = 6.92, p = 1.7 × 10−33), PLOD2 (FC = 4.89, p = 7.4 × 10−33), PFKP (FC = 4.2, p = 4.3 × 10−56), IGFBP3 (FC = 2.28, p = 2.1 × 10−31), and VEGFA (FC = 3.12, p = 3 × 10−32), had significant differences between normal kidney and ccRCC in the CPTAC study. Here, VEGFA is linked to nonpapillary renal cell carcinoma.