Other recurrently mutated genes in cutaneous melanomas include the proto-oncogene c-Kit (KIT), telomerase reverse transcriptase (TERT), Rac family small GTPase 1 (Rac1), phosphatase and tensin homolog (PTEN), and tumor protein p53 (TP53) [42,43,44]. Here, PTEN is linked to cutaneous melanoma.