We have tested the action of the antipsychotic compound on a pharmacological model of psychosis; however, further analyses of the gene expression connectome could take advantage of genetic rodent models mirroring persistent reorganization of neural circuitry characteristic of schizophrenia, such as disrupted in schizophrenia 1 (DISC1) L100P mutants [43]. The gene discussed is DISC1; the disease is schizophrenia.