BBC3 and liver cancer: Furthermore, in liver cancer [44], miR-483-3p has been found to act as an oncogenic and antiapoptotic factor by means of the inhibition of the p53 Upregulated Modulator of Apoptosis (PUMA), a pro-apoptotic protein that, under physiological conditions, blocks the antiapoptotic action of B-Cell CLL/Lymphoma 2 (BCL2) [46].