MMP3 and adenoma: The analysis of colonic adenomatous nodes revealed low expression of all the explored acute colitis-associated key genes: the expression levels of C3, Tyrobp, Mmp3, Mmp9, and Timp1 in adenoma tissue were 26.3, 3.4, 20.8, 11.9, and 27.7 times lower than those in the samples with acute colitis (Figure 3D).