We found in the literature that ADMA showed a positive correlation with the incidence of LVDD [18] and N-terminal pro-brain NP (NT-proBNP) values [19], and, similarly to NT-proBNP, can further improve the stratification of the risk of cardiac decompensation, major adverse CV events, and mortality in patients with HF [20,21]. The gene discussed is NPPB; the disease is hydrops fetalis.