The results showed that the mediating effect regression coefficient of central obesity on the relationship between DII score, HEI score and hs-CRP was statistically significant (βDII = 0.007, 95%CI: 0.001, 0.014; βHEI = −0.002, 95%CI: −0.003,−0.001), accounting for 15.24% and 26.87% of the total effect, respectively. This evidence concerns the gene CRP and Abdominal obesity.