In Phase II, the two diagnostic groups (i.e., CNI, MCI) were comparable in Body Mass Index, gender ratio, lifestyle habits, previous occupation, frequency of persons living alone, overall health (as indexed by the number of current major medical morbidities), and family history of dementia (see Table 1), with the exception of age (CNI < MCI, p < 0.001) and frequency of APOE ε4 carriers (CNI < MCI, p = 0.04). Here, APOE is linked to dementia.