GALK1 and galactosemia: Galactosemia is a genetic disease in which galactose accumulates in the body due to a deficiency of enzymes galactokinase (GALK), UDP-galactose 4-epimerase (GALE), and galactose-1-phosphate uridylyltransferase (GALT) involved in the metabolic process that converts galactose into glucose.