TFF2 and gastric ulcer: In recent years, studies have shown that R. roxburghii juice has obvious therapeutic effects on gastric ulcer, and its mechanism may be related to inhibiting gastric acid, pepsin, MDA, and other damage factors, increasing the content of trefoil factor-2 (TFF-2), epidermal growth factor (EGF), and vasoactive substance NO, promoting protective factors such as SOD and prostaglandin E2 (PGE2), producing antioxidant free radicals and anti-inflammatory effects so as to repair and improve gastric mucosa [118,119].