Studies have shown that R. roxburghii can significantly reduce the contents of TC and triglyceride (TG) in serum, enhance the antioxidant activity of LDL, increase the level of HDL, reduce the damage of lipid metabolism and oxidation to arterial intima, adjust lipid metabolism of hyperlipidemia, and improve SOD activity, so as to prevent atherosclerotic plaques in arterial intima [90,91]. This evidence concerns the gene SOD1 and hyperlipidemia.