Second, the Asian Cancer Research Group (ACRG, 2015) also identified four molecular subtypes: MSI (microsatellite unstable), MSS/EMT (microsatellite table, epithelial-mesenchymal transition), MSS/TP53+ (tumor protein 53 aberrant) and MSS/TP53- (tumor protein 53 inactive). This evidence concerns the gene TP53 and cancer.