With the routine availability in our clinical practice of NGS and transcriptome sequencing panels (e.g., Caris) as part of sarcoma pathology and molecular reports detailing the presence of fusion genes, we have developed practical tools to investigate whether identical, similar, or very different peptides are made from the EWS-partner fusion genes in Ewing sarcoma and DSRCT in our clinical population. Here, EWSR1 is linked to Ewing sarcoma.