Since then, and recently accelerated by the advent of next-generation sequencing (NGS), a growing number of genes have been associated with germline predisposition to myeloid malignancies, including the ANKRD26 [2,3,4], ETV6 [5,6,7], CEBPA [8], DDX41 [9], GATA2 [10], RBBP6 [11], TERT, TERC [12], and, most recently the SAMD9 [13] and SAMD9L genes [14,15]. Here, GATA2 is linked to myeloid neoplasm.