GATA2 and hyperinsulinemic hypoglycemia, familial, 4: Pulmonary dysfunction is a common finding in up to 50% of patients with GATA2 deficiency [90], even in the absence of hematopoietic disease, leading to progressive compromised pulmonary function with diffusion defects, ventilatory defects, or a mixed pattern, along with significant clinical and radiographic disease [41,71,76,91].