ERBB2 and neoplasm: The main patient characteristics were equally distributed between chemotherapy arms (Table 1): median age was 53 yrs (21–70), 41.4% of patients were peri- or premenopausal, median tumor size was 1.9 cm, grade 3 was seen in 53.8%, negative steroid hormone receptor status in 30.1% and positive HER2-status in 20.0%, and mastectomy was performed in 11% of all tumors.