In that study, the authors found that the oncogene SPEN induces miR-4652-3p expression in nasopharyngeal carcinoma (NPC) by activation of the PI3K/AKT/c-JUN signaling and that miR-4652-3p targets and downregulates HIPK2 [69]. Here, AKT1 is linked to nasopharyngeal carcinoma.