This study is the first to investigate soluble forms of the macrophage markers SIRPα, LILRB1, CD163, and CD206 in sarcoma, and its conclusions are in accordance with a large study conducted by Dancsok showing that SIRPα in tissue samples is an adverse prognostic factor for soft tissue sarcomas [18]. Here, LILRB1 is linked to soft tissue sarcoma.