CTLA4 and Miyoshi myopathy: A retrospective multicentre international study and a multicentre Japanese study including 545 and 329 advanced or unresectable stage II MM treated with anti-PD1 (pembrolizumab) alone or combined with anti-CTLA-4 (ipilimumab) state that these therapies have lower efficacy than in CM (response rate of 30% and 26% in MM), and that response is also less durable (mean duration of response (mDoR) is 25 months) [29,30].