Various studies have reported that CAMs, including CD44, CD138, ICAM-1 [18,19,20,21,22], VCAM-1 [23], CD11A, CD49D [21,24], α4β1 [25],and CXC motif chemokine receptors (CXCR) integrin [26], are associated with adhesion of MM cells to bone marrow stromal cells (BMSC), which leads to MM stemness and participate in BTZ resistance of MM. The gene discussed is CD44; the disease is Miyoshi myopathy.