A difference in the expression of IL8 in the epithelium in patients with OSCC and OPMD was reported, where IL8 was present in all the layers of the epithelium in 64% of the OSCC group, but not in the control group, and no marked increase in expression in the OPMD tissue specimens was observed [24]. Here, CXCL8 is linked to oculopharyngeal muscular dystrophy.