FOXP3 and neoplasm: Mukherjee et al. and Cho et al. also observed a positive relationship between low CD8+ TIL density and larger size of tumors in a series of oral SCCs [59,60], while Green et al., Lequerica-Fernández et al., and Wang et al. agree with our results about the positive relation of FOXP3+ lymphocytic density and tumor size [42,61,62].