CD8A and neoplasm: LDH5 was directly related to high CD4+ TILs in the invading tumor front (p = 0.05, r = 0.26), while nuclear LDH5 expression was directly linked with FOXP3+ TILs (p = 0.01, r = 0.31; Figure 4c) and FOXP3/CD8 ratio (p = 0.03, r = 0.27).