Chemokine CXCL10, as an interferon-inducible protein, is most likely involved in the thermal-ablation-induced expression of CXCL10 by TAM1, which stimulates interferon secretion and recruits CXCR3+CD8+T cells to infiltrate into tumor tissues, thus exerting anti-tumor effects. The gene discussed is CXCL10; the disease is neoplasm.