Non-syndromic hereditary hyperparathyroidism, called familial isolated hyperparathyroidism (FIHP), can be caused by the incomplete manifestation of mutations of syndrome-related genes such as MEN-1, CDC73, GCM2, CDKN1A, CDKN1B, or CDKN2C [17,21]. The gene discussed is MEN1; the disease is familial isolated hyperparathyroidism.