To study the role of MAPK15 in lung cancer, we analyzed the relationship between MAPK15 and clinical–pathological parameters such as age, gender, depth of tumor invasion, lymph node metastasis, distant metastasis, tumor differentiation, clinical stage, etc. We found that there was a positive correlation between MAPK15 expression and lymph node metastasis (p = 0.012) as well as clinical stage (p = 0.033) (Supplementary Table S2). The gene discussed is MAPK15; the disease is lung cancer.