In human-derived 9 colon cancer cell lines (DLD1, SW480, HCT116, KM12C, Lovo, HT29, WiDr, Caco2, and KM12SM) and a Balb/c mouse-derived colon cancer cell line (CT26), LAT1 mRNA expression was high in HT29 and CT26 (relative expression: 17.8 and 22, respectively), intermediate in SW480 and HCT116, and low in DLD1 and Lovo (relative expression: 0.3 and 1.5, respectively). Here, SLC7A5 is linked to malignant colon neoplasm.