Given some evidence of a causative link between DMD downregulation and phenotypic changes in tumor cells [17,23] and that alterations in Duchenne, such as increased cell proliferation, abnormalities in adhesion, migration, and invasion [11,12] are commonly associated with malignancy, transcriptomes of primary tumor samples as well as tumor cell lines with low vs. high levels of DMD gene expression were compared. This evidence concerns the gene DMD and neoplasm.