Furthermore, functional enrichment tests of the dystrophin protein-protein interaction network constructed using high confidence PPI information demonstrated that the enriched functional terms were consistent with the pathways found to be significantly enriched in the aforementioned comparisons of primary tumors, tumor cell lines, and DMD skeletal muscle: extracellular matrix organization (p = 1.10 × 10−18), axon guidance (p = 9.45 × 10−10), focal adhesion (p = 3.27 × 10−14), and PI3K-Akt signaling pathways (p = 9.27 × 10−9) (Supplementary Figure S6). Here, AKT1 is linked to neoplasm.