VEGFA and neoplasm: In addition, GALR2-RAP1-p38MAPK-mediated inactivation of Tristetraprolin(TTP), an RNA-binding protein that promotes decay of transcripts of proangiogenic factors (including IL-6, VEGF, IL-8) [135,136,137], and then induces angiogenesis, which facilitates tumor progression by supplying oxygen and nutrients [138].