Malignant prostate epithelial cells were reported to overexpress NGF and BDNF, but also the corresponding TrkB and TrkC receptors, which may be related to the migration of malignant cells, frequently occurs along nerves within the prostate, because it may provide abundant neurotrophins to act as chemoattractive guidance clues for tumor migration [111,112]. This evidence concerns the gene NGF and neoplasm.