MSLN and cancer: Several clinical trials (NCT04577326, NCT03608618, NCT03323944, NCT03267173, NCT03198052, NCT03054298, NCT02959151, NCT02706782 and NCT02414269) have been conducted to assess the effectiveness and safety of anti-MSLN CAR-T cells in cancer patients with positive results for MSLN administered via the intrathoracic, intraperitoneal, intratumoral or vascular routes.