Using flow cytometry to detect specific markers that can predict infection in 20 febrile patients of our study subjects (13 FP and 7 FN) and 9 HC subjects, three different surface markers, CD10 (percent positive), CD64 mean fluorescence intensity (MFI), and CXCR4 MFI demonstrated a significant distinction between the FP and FN groups. The gene discussed is MME; the disease is infection.