Tumors including OC are able to escape the intrinsic anti-tumor activity of the immune system by means of so-called immune evasion strategies [47,48] and cancer immunoediting, often attributed to the interaction of tumor cells with tumor-infiltrating lymphocytes as well as immunomodulatory factors such as PD-L1, CTLA-4, and CXCR4 [49,50]. The gene discussed is CTLA4; the disease is neoplasm.