Until now, epitranscriptomic mechanisms for silencing UMOD gene expression have not been considered but could be of great interest for ccRCC as well as other urological (e.g., urinary tract infections, urolithiasis) and nephrological (e.g., autosomal dominant tubulointerstitial kidney disease, chronic kidney disease) diseases [41,44]. The gene discussed is UMOD; the disease is nonpapillary renal cell carcinoma.