Expression boxplots of the three validated m6A-driven key genes in TCGA-ccRCC are shown in Figure 2A. All cancer patients in the overall TCGA-KIRC cohort that simultaneously showed significantly high expression of NDUFA4L2 and NXPH4 (hyper-up) and significantly low UMOD expression (hypo-down) were identified and grouped together in the NNU panel. This evidence concerns the gene COXFA4L2 and cancer.