UMOD and nonpapillary renal cell carcinoma: By binarising the expression differences of the matching and significantly validated dysregulated hyper-up and hypo-down genes in 72 TCGA-ccRCC samples with corresponding normal controls, a consistent and homogeneous expression pattern (expression mismatch < 10%) was confirmed for three (11.67%) of the 35 predefined m6A genes, namely NDUFA4L2, NXPH4, and UMOD (Supplementary Figure S1).