LRRK2 and Parkinson disease: For this, nervous and hepatic tissues extracted from mice with genetic model (GS-PD, due to G2019S-LRRK2 mutation) or acute intoxication model (ai-PD, WT mice treated with 6-OHDA) were analyzed to observe the complete metabolomic profile in striatum (Table S1) and hepatocyte cells (Table S2).